Transdermal Delivery of Active Principles with Pulsed RF Contact Diathermy - A Narrative Review

The transdermal delivery of drugs and, in more general terms, active principles can be performed by iontophoresis and/or electroporation. advantages a local treatment vs. other intake methods are well known as it reduces the systemic involvement and therefore contraindications. To perform exploiting electroporation effect there is nowadays specific variant medical device used physiotherapy: Medium Frequency Resistive/Capacitive contact Diathermy. adoption power control Pulse Width Modulation applied current adds to also this capability great potential rehabilitation aesthetic medicine treatments. theoretic approach discussed applications suggestions being given.